By discerning specific VOC patterns in breath, Super Nose becomes a crucial ally in the early detection of respiratory diseases, including but not limited to asthma, cancer, tuberculosis, cystic fibrosis, and drug-related illnesses.
In the landscape of medical and pharmaceutical sciences, Super Nose, a groundbreaking iteration of electronic nose (eNose) technology crafted by iSenso Group, stands poised at the forefront of transformative advancements. Rooted in the rich history of biochemical and biomolecular diagnostic methods, Super Nose emerges as a pioneering tool with unparalleled applications, particularly in non-invasive breath analysis, redefining the paradigms of disease diagnosis, monitoring, and pharmaceutical research.
An article from 2009 by Alphus D. Wilson and Manuela Baietto, which is still being used for present studies, stated the following:
“One of the most disputed yet promising applications of electronic nose technologies is for the early detection and diagnosis of oncologic diseases, in particular lung cancer. Since 1971, it has become well known that hundreds of VOCs are present in the human breath [177], and that some of these compounds are associated with certain diseases [178–180]. O’Neil et al. [181] reported higher levels of alkanes (hexane and methylpentane in particular) in the breath of patients affected by lung cancer; later confirmed by Philips et al. [182,183]. SEE MORE The initial work to evaluate the feasibility of the electronic nose in detecting these cancer-marker compounds was done by Di Natale et al. [184]. They collected breath samples from 60 individuals: 35 of which were affected by lung cancer, 9 had just had surgical therapy and 18 were used as controls. Two more individuals were measured before and after surgical therapy. The electronic nose could successfully detect 100% of lung cancer affected patients, 94% of controls and 44% of post-surgery patients (the others were classified as healthy controls). This study confirmed that the electronic nose could successfully identify eleven diagnostic VOCs that were validated as indicators or chemical markers of lung cancer.”
Revolutionizing Diagnostic Procedures
Traditionally, diagnostic methodologies in medicine have centered around blood and urine analysis. Super Nose, with its innovative eNose technology, introduces a paradigm shift by integrating noninvasive breath analysis into existing examination procedures. This approach proves to be painless, cost-effective, and easily accessible for a diverse range of patients, including the sick, children, and the elderly.
Exploring the Potential of Exhaled Breath Analysis: A Historical Perspective
The roots of exhaled breath analysis trace back to the teachings of Hippocrates, who recognized the clinical significance of specific odors, such as fetor hepaticus, associated with hepatic diseases. The compounds responsible for these odors were later unveiled through gas chromatography coupled with mass spectrometry (GC-MS). For instance, patients with hepatic conditions exhibit distinctive VOC profiles in their breath, including higher levels of dimethyl sulfide, acetone, 2-butanone, and 2-pentanone, alongside lower levels of indole and dimethyl selenide.
Super Nose in Respiratory Diseases: A Precision Approach
In the vast area of medical applications, Super Nose particularly excels in addressing respiratory diseases, leveraging its array of sensors designed for the precise detection and analysis of volatile organic compounds (VOCs). Diverging from conventional methods like gas chromatography and mass spectrometry, it employs pattern recognition to distinguish VOC spectra, offering unparalleled accuracy in medical applications.
Super Nose represents a revolutionary force in the medical and pharmaceutical industries, ushering in a new era of precision diagnostics, personalized treatment plans, and innovative pharmaceutical research. This device promises to redefine the standards of healthcare and increase life expectancy.
Beyond respiratory diseases, Super Nose extends its prowess to revolutionize medical and pharmaceutical practices through its myriad advantages: